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A Simple Method to Reduce both Lactic Acid and Ammonium Production in Industrial Animal Cell Culture
Fed-batch animal cell culture is the most common method for commercial production of recombinant proteins. However, higher cell densities in these platforms are still limited due to factors such as excessive ammonium production, lactic acid production, nutrient limitation, and/or hyperosmotic stress...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855607/ https://www.ncbi.nlm.nih.gov/pubmed/29382079 http://dx.doi.org/10.3390/ijms19020385 |