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The Impact of Aging on Cardio and Cerebrovascular Diseases
A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855703/ https://www.ncbi.nlm.nih.gov/pubmed/29415476 http://dx.doi.org/10.3390/ijms19020481 |
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author | Izzo, Carmine Carrizzo, Albino Alfano, Antonia Virtuoso, Nicola Capunzo, Mario Calabrese, Mariaconsiglia De Simone, Eros Sciarretta, Sebastiano Frati, Giacomo Oliveti, Marco Damato, Antonio Ambrosio, Mariateresa De Caro, Francesco Remondelli, Paolo Vecchione, Carmine |
author_facet | Izzo, Carmine Carrizzo, Albino Alfano, Antonia Virtuoso, Nicola Capunzo, Mario Calabrese, Mariaconsiglia De Simone, Eros Sciarretta, Sebastiano Frati, Giacomo Oliveti, Marco Damato, Antonio Ambrosio, Mariateresa De Caro, Francesco Remondelli, Paolo Vecchione, Carmine |
author_sort | Izzo, Carmine |
collection | PubMed |
description | A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best therapeutic strategy to adopt, without neglecting all the risk factors associated with advanced age. Of course, the better way should always be understanding risk-to-benefit ratio, maintenance of independence and reduction of symptoms. Although improvements in treatment of cardiovascular diseases in the elderly population have increased the survival rate, several studies are needed to understand the best management option to improve therapeutic outcomes. The aim of this review is to give a 360° panorama on what goes on in the fragile ecosystem of elderly, why it happens and what we can do, right now, with the tools at our disposal to slow down aging, until new discoveries on aging, cardio and cerebrovascular diseases are at hand. |
format | Online Article Text |
id | pubmed-5855703 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-58557032018-03-20 The Impact of Aging on Cardio and Cerebrovascular Diseases Izzo, Carmine Carrizzo, Albino Alfano, Antonia Virtuoso, Nicola Capunzo, Mario Calabrese, Mariaconsiglia De Simone, Eros Sciarretta, Sebastiano Frati, Giacomo Oliveti, Marco Damato, Antonio Ambrosio, Mariateresa De Caro, Francesco Remondelli, Paolo Vecchione, Carmine Int J Mol Sci Review A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best therapeutic strategy to adopt, without neglecting all the risk factors associated with advanced age. Of course, the better way should always be understanding risk-to-benefit ratio, maintenance of independence and reduction of symptoms. Although improvements in treatment of cardiovascular diseases in the elderly population have increased the survival rate, several studies are needed to understand the best management option to improve therapeutic outcomes. The aim of this review is to give a 360° panorama on what goes on in the fragile ecosystem of elderly, why it happens and what we can do, right now, with the tools at our disposal to slow down aging, until new discoveries on aging, cardio and cerebrovascular diseases are at hand. MDPI 2018-02-06 /pmc/articles/PMC5855703/ /pubmed/29415476 http://dx.doi.org/10.3390/ijms19020481 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Izzo, Carmine Carrizzo, Albino Alfano, Antonia Virtuoso, Nicola Capunzo, Mario Calabrese, Mariaconsiglia De Simone, Eros Sciarretta, Sebastiano Frati, Giacomo Oliveti, Marco Damato, Antonio Ambrosio, Mariateresa De Caro, Francesco Remondelli, Paolo Vecchione, Carmine The Impact of Aging on Cardio and Cerebrovascular Diseases |
title | The Impact of Aging on Cardio and Cerebrovascular Diseases |
title_full | The Impact of Aging on Cardio and Cerebrovascular Diseases |
title_fullStr | The Impact of Aging on Cardio and Cerebrovascular Diseases |
title_full_unstemmed | The Impact of Aging on Cardio and Cerebrovascular Diseases |
title_short | The Impact of Aging on Cardio and Cerebrovascular Diseases |
title_sort | impact of aging on cardio and cerebrovascular diseases |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855703/ https://www.ncbi.nlm.nih.gov/pubmed/29415476 http://dx.doi.org/10.3390/ijms19020481 |
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