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The Impact of Aging on Cardio and Cerebrovascular Diseases

A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best...

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Autores principales: Izzo, Carmine, Carrizzo, Albino, Alfano, Antonia, Virtuoso, Nicola, Capunzo, Mario, Calabrese, Mariaconsiglia, De Simone, Eros, Sciarretta, Sebastiano, Frati, Giacomo, Oliveti, Marco, Damato, Antonio, Ambrosio, Mariateresa, De Caro, Francesco, Remondelli, Paolo, Vecchione, Carmine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855703/
https://www.ncbi.nlm.nih.gov/pubmed/29415476
http://dx.doi.org/10.3390/ijms19020481
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author Izzo, Carmine
Carrizzo, Albino
Alfano, Antonia
Virtuoso, Nicola
Capunzo, Mario
Calabrese, Mariaconsiglia
De Simone, Eros
Sciarretta, Sebastiano
Frati, Giacomo
Oliveti, Marco
Damato, Antonio
Ambrosio, Mariateresa
De Caro, Francesco
Remondelli, Paolo
Vecchione, Carmine
author_facet Izzo, Carmine
Carrizzo, Albino
Alfano, Antonia
Virtuoso, Nicola
Capunzo, Mario
Calabrese, Mariaconsiglia
De Simone, Eros
Sciarretta, Sebastiano
Frati, Giacomo
Oliveti, Marco
Damato, Antonio
Ambrosio, Mariateresa
De Caro, Francesco
Remondelli, Paolo
Vecchione, Carmine
author_sort Izzo, Carmine
collection PubMed
description A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best therapeutic strategy to adopt, without neglecting all the risk factors associated with advanced age. Of course, the better way should always be understanding risk-to-benefit ratio, maintenance of independence and reduction of symptoms. Although improvements in treatment of cardiovascular diseases in the elderly population have increased the survival rate, several studies are needed to understand the best management option to improve therapeutic outcomes. The aim of this review is to give a 360° panorama on what goes on in the fragile ecosystem of elderly, why it happens and what we can do, right now, with the tools at our disposal to slow down aging, until new discoveries on aging, cardio and cerebrovascular diseases are at hand.
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spelling pubmed-58557032018-03-20 The Impact of Aging on Cardio and Cerebrovascular Diseases Izzo, Carmine Carrizzo, Albino Alfano, Antonia Virtuoso, Nicola Capunzo, Mario Calabrese, Mariaconsiglia De Simone, Eros Sciarretta, Sebastiano Frati, Giacomo Oliveti, Marco Damato, Antonio Ambrosio, Mariateresa De Caro, Francesco Remondelli, Paolo Vecchione, Carmine Int J Mol Sci Review A growing number of evidences report that aging represents the major risk factor for the development of cardio and cerebrovascular diseases. Understanding Aging from a genetic, biochemical and physiological point of view could be helpful to design a better medical approach and to elaborate the best therapeutic strategy to adopt, without neglecting all the risk factors associated with advanced age. Of course, the better way should always be understanding risk-to-benefit ratio, maintenance of independence and reduction of symptoms. Although improvements in treatment of cardiovascular diseases in the elderly population have increased the survival rate, several studies are needed to understand the best management option to improve therapeutic outcomes. The aim of this review is to give a 360° panorama on what goes on in the fragile ecosystem of elderly, why it happens and what we can do, right now, with the tools at our disposal to slow down aging, until new discoveries on aging, cardio and cerebrovascular diseases are at hand. MDPI 2018-02-06 /pmc/articles/PMC5855703/ /pubmed/29415476 http://dx.doi.org/10.3390/ijms19020481 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Izzo, Carmine
Carrizzo, Albino
Alfano, Antonia
Virtuoso, Nicola
Capunzo, Mario
Calabrese, Mariaconsiglia
De Simone, Eros
Sciarretta, Sebastiano
Frati, Giacomo
Oliveti, Marco
Damato, Antonio
Ambrosio, Mariateresa
De Caro, Francesco
Remondelli, Paolo
Vecchione, Carmine
The Impact of Aging on Cardio and Cerebrovascular Diseases
title The Impact of Aging on Cardio and Cerebrovascular Diseases
title_full The Impact of Aging on Cardio and Cerebrovascular Diseases
title_fullStr The Impact of Aging on Cardio and Cerebrovascular Diseases
title_full_unstemmed The Impact of Aging on Cardio and Cerebrovascular Diseases
title_short The Impact of Aging on Cardio and Cerebrovascular Diseases
title_sort impact of aging on cardio and cerebrovascular diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855703/
https://www.ncbi.nlm.nih.gov/pubmed/29415476
http://dx.doi.org/10.3390/ijms19020481
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