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Consecutive Isoproterenol and Adenosine Treatment Confers Marked Protection against Reperfusion Injury in Adult but Not in Immature Heart: A Role for Glycogen

Consecutive treatment of adult rat heart with isoproterenol and adenosine (Iso/Aden), known to consecutively activate PKA/PKC signaling, is cardioprotective against ischemia and reperfusion (I/R). Whether this is cardioprotective in an immature heart is unknown. Langendorff–perfused hearts from adul...

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Detalles Bibliográficos
Autores principales: Lewis, Martin, Szobi, Adrian, Balaska, Dirki, Khaliulin, Igor, Adameova, Adriana, Griffiths, Elinor, Orchard, Clive H., Suleiman, M.-Saadeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855716/
https://www.ncbi.nlm.nih.gov/pubmed/29414860
http://dx.doi.org/10.3390/ijms19020494

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