Histone Deacetylase Inhibitor Induced Radiation Sensitization Effects on Human Cancer Cells after Photon and Hadron Radiation Exposure

Suberoylanilide hydroxamic acid (SAHA) is a histone deacetylase inhibitor, which has been widely utilized throughout the cancer research field. SAHA-induced radiosensitization in normal human fibroblasts AG1522 and lung carcinoma cells A549 were evaluated with a combination of γ-rays, proton, and ca...

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Detalles Bibliográficos
Autores principales: Gerelchuluun, Ariungerel, Maeda, Junko, Manabe, Eri, Brents, Colleen A., Sakae, Takeji, Fujimori, Akira, Chen, David J., Tsuboi, Koji, Kato, Takamitsu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855718/
https://www.ncbi.nlm.nih.gov/pubmed/29414878
http://dx.doi.org/10.3390/ijms19020496

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