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High-Fat-Diet-Induced Obesity Produces Spontaneous Ventricular Arrhythmias and Increases the Activity of Ryanodine Receptors in Mice

Ventricular arrhythmias are a common cause of sudden cardiac death, and their occurrence is higher in obese subjects. Abnormal gating of ryanodine receptors (RyR2), the calcium release channels of the sarcoplasmic reticulum, can produce ventricular arrhythmias. Since obesity promotes oxidative stres...

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Detalles Bibliográficos
Autores principales:	Sánchez, Gina, Araneda, Felipe, Peña, Juan Pedro, Finkelstein, José Pablo, Riquelme, Jaime A., Montecinos, Luis, Barrientos, Genaro, Llanos, Paola, Pedrozo, Zully, Said, Matilde, Bull, Ricardo, Donoso, Paulina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855755/ https://www.ncbi.nlm.nih.gov/pubmed/29439404 http://dx.doi.org/10.3390/ijms19020533

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