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Site-Specific Cleavage by Topoisomerase 2: A Mark of the Core Centromere
In addition to its roles in transcription and replication, topoisomerase 2 (topo 2) is crucial in shaping mitotic chromosomes and in ensuring the orderly separation of sister chromatids. As well as its recruitment throughout the length of the mitotic chromosome, topo 2 accumulates at the primary con...
Autores principales: | Mills, Walter E., Spence, Jennifer M., Fukagawa, Tatsuo, Farr, Christine J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855756/ https://www.ncbi.nlm.nih.gov/pubmed/29439406 http://dx.doi.org/10.3390/ijms19020534 |
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