Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies

Alzheimer’s disease is the most fatal neurodegenerative disorder characterized by the aggregation and deposition of Amyloid β (Aβ) oligomers in the brain of patients. Two principal variants of Aβ exist in humans: Aβ(1–40) and Aβ(1–42). The former is the most abundant in the plaques, while the latter...

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Detalles Bibliográficos
Autores principales: Grasso, Gianvito, Rebella, Martina, Muscat, Stefano, Morbiducci, Umberto, Tuszynski, Jack, Danani, Andrea, Deriu, Marco A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855793/
https://www.ncbi.nlm.nih.gov/pubmed/29443891
http://dx.doi.org/10.3390/ijms19020571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855793/
https://www.ncbi.nlm.nih.gov/pubmed/29443891
http://dx.doi.org/10.3390/ijms19020571

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