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Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies
Alzheimer’s disease is the most fatal neurodegenerative disorder characterized by the aggregation and deposition of Amyloid β (Aβ) oligomers in the brain of patients. Two principal variants of Aβ exist in humans: Aβ(1–40) and Aβ(1–42). The former is the most abundant in the plaques, while the latter...
Autores principales: | Grasso, Gianvito, Rebella, Martina, Muscat, Stefano, Morbiducci, Umberto, Tuszynski, Jack, Danani, Andrea, Deriu, Marco A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855793/ https://www.ncbi.nlm.nih.gov/pubmed/29443891 http://dx.doi.org/10.3390/ijms19020571 |
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