The Connexin Mimetic Peptide Gap27 and Cx43-Knockdown Reveal Differential Roles for Connexin43 in Wound Closure Events in Skin Model Systems

In the epidermis, remodelling of Connexin43 is a key event in wound closure. However, controversy between the role of connexin channel and non-channel functions exist. We compared the impact of SiRNA targeted to Connexin43 and the connexin mimetic peptide Gap27 on scrape wound closure rates and hemi...

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Detalles Bibliográficos
Autores principales: Faniku, Chrysovalantou, O’Shaughnessy, Erin, Lorraine, Claire, Johnstone, Scott R., Graham, Annette, Greenhough, Sebastian, Martin, Patricia E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855826/
https://www.ncbi.nlm.nih.gov/pubmed/29463027
http://dx.doi.org/10.3390/ijms19020604

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