Telomere Length Maintenance in Cancer: At the Crossroad between Telomerase and Alternative Lengthening of Telomeres (ALT)

Eukaryotic cells undergo continuous telomere shortening as a consequence of multiple rounds of replications. During tumorigenesis, cells have to acquire telomere DNA maintenance mechanisms (TMMs) in order to counteract telomere shortening, to preserve telomeres from DNA damage repair systems and to...

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Detalles Bibliográficos
Autores principales: De Vitis, Marco, Berardinelli, Francesco, Sgura, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855828/
https://www.ncbi.nlm.nih.gov/pubmed/29463031
http://dx.doi.org/10.3390/ijms19020606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855828/
https://www.ncbi.nlm.nih.gov/pubmed/29463031
http://dx.doi.org/10.3390/ijms19020606

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