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Regulation of transferrin receptor-1 mRNA by the interplay between IRE-binding proteins and miR-7/miR-141 in the 3′-IRE stem–loops

Intracellular iron is tightly regulated by coordinated expression of iron transport and storage genes, such as transferrin receptor-1 (TfR1) and ferritin. They are primarily regulated by iron through iron-induced dissociation of iron-regulatory proteins (IRPs) from iron-responsive elements (IREs) in...

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Detalles Bibliográficos
Autores principales: Miyazawa, Masaki, Bogdan, Alexander R., Hashimoto, Kazunori, Tsuji, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855948/
https://www.ncbi.nlm.nih.gov/pubmed/29295890
http://dx.doi.org/10.1261/rna.063941.117