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CD4+ αβ T cell infiltration into the leptomeninges of lumbar dorsal roots contributes to the transition from acute to chronic mechanical allodynia after adult rat tibial nerve injuries

BACKGROUND: Antigen-specific and MHCII-restricted CD4+ αβ T cells have been shown or suggested to play an important role in the transition from acute to chronic mechanical allodynia after peripheral nerve injuries. However, it is still largely unknown where these T cells infiltrate along the somatos...

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Detalles Bibliográficos
Autores principales: Du, Bin, Ding, You-Quan, Xiao, Xia, Ren, Hong-Yi, Su, Bing-Yin, Qi, Jian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855984/
https://www.ncbi.nlm.nih.gov/pubmed/29544518
http://dx.doi.org/10.1186/s12974-018-1115-7