Cargando…

Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients

BACKGROUND: Multi-organ failure occurs during critical illness and is mediated in part by destructive neutrophil-to-endothelial interactions. The β2 integrin receptor, CR3 (complement receptor 3; Mac-1; CD11b/CD18), which binds endothelial intercellular adhesion molecule-1 (ICAM-1), plays a key role...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dickinson, Catherine M., LeBlanc, Brian W., Edhi, Muhammad M., Heffernan, Daithi S., Faridi, Mohd. Hafeez, Gupta, Vineet, Cioffi, William G., O’Brien, Xian, Reichner, Jonathan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5855997/ https://www.ncbi.nlm.nih.gov/pubmed/29568527 http://dx.doi.org/10.1186/s40560-018-0289-5

Ejemplares similares

Neutrophils from critically ill septic patients mediate profound loss of endothelial barrier integrity
por: Fox, Elizabeth D, et al.
Publicado: (2013)

Neutrophil Integrins and Matrix Ligands and NET Release
por: O’Brien, Xian M., et al.
Publicado: (2016)

The complement receptor 3 (CD11b/CD18) agonist Leukadherin‐1 suppresses human innate inflammatory signalling
por: Roberts, A. L., et al.
Publicado: (2016)

Protective Effects of Leukadherin1 in a Rat Model of Targeted Experimental Autoimmune Encephalomyelitis (EAE): Possible Role of P47phox and MDA Downregulation
por: Hemmati, Sara, et al.
Publicado: (2020)

Failure to normalize lymphopenia following trauma is associated with increased mortality, independent of the leukocytosis pattern
por: Heffernan, Daithi S, et al.
Publicado: (2012)

Describing Directional Cell Migration with a Characteristic Directionality Time
por: Loosley, Alex J., et al.
Publicado: (2015)

Lymphocyte HVEM/BTLA co-expression after critical illness demonstrates severity indiscriminate upregulation, impacting critical illness-induced immunosuppression
por: Wakeley, Michelle E., et al.
Publicado: (2023)

Changes in the process of alternative RNA splicing results in soluble B and T lymphocyte attenuator with biological and clinical implications in critical illness
por: Monaghan, Sean F., et al.
Publicado: (2018)

Mechanosensitive traction force generation is regulated by the neutrophil activation state
por: Witt, Hadley, et al.
Publicado: (2023)

Leukadherin-1-Mediated Activation of CD11b Inhibits LPS-Induced Pro-inflammatory Response in Macrophages and Protects Mice Against Endotoxic Shock by Blocking LPS-TLR4 Interaction
por: Yao, Xiaoying, et al.
Publicado: (2019)

Soluble programmed cell death receptor-1 (sPD-1): a potential biomarker with anti-inflammatory properties in human and experimental acute respiratory distress syndrome (ARDS)
por: Monaghan, Sean F., et al.
Publicado: (2016)

Peritoneal free air due to evacuation of pneumobilia in blunt abdominal trauma
por: Howley, Isaac, et al.
Publicado: (2010)

Machine learning methods to predict presence of residual cancer following hysterectomy
por: Ganguli, Reetam, et al.
Publicado: (2022)

Wandering spleen in a geriatric patient – a rare presentation of gastric volvulus
por: Gandhi, Christy, et al.
Publicado: (2019)

Uterine tumor resembling ovarian sex cord tumor (UTROSCT), case report with literature review
por: Hashmi, Atif Ali, et al.
Publicado: (2014)

Spectrum of intra-thoracic lesion detected by computed tomography guided fine needle aspiration biopsy
por: Naqvi, Hanna, et al.
Publicado: (2013)

Effect of bupivacaine soaked gauze in postoperative pain relief in laparoscopic cholecystectomy: a prospective observational controlled trial in 120 patients
por: Ahmad, Aman, et al.
Publicado: (2015)

B and T lymphocyte attenuator expression on CD4(+) T-cells associates with sepsis and subsequent infections in ICU patients
por: Shubin, Nicholas J, et al.
Publicado: (2013)

A large parosteal ossifying lipoma of lower limb encircling the femur
por: Hashmi, Atif Ali, et al.
Publicado: (2014)

Fibro-osseous pseudotumor of the digit presenting as an ulcerated lesion: a case report
por: Hashmi, Atif Ali, et al.
Publicado: (2014)

A large mediastinal benign myoepithelioma effacing the entire hemithorax: case report with literature review
por: Hashmi, Atif Ali, et al.
Publicado: (2015)

Mutiple keratocystic odontogenic tumors (KCOT) in a patient with Gorlin syndrome: a case report with late presentation and absence of skin manifestations
por: Hashmi, Atif Ali, et al.
Publicado: (2016)

Context-Dependent Role of Vinculin in Neutrophil Adhesion, Motility and Trafficking
por: Wilson, Zachary S., et al.
Publicado: (2020)

Program Cell Death Receptor-1-Mediated Invariant Natural Killer T-Cell Control of Peritoneal Macrophage Modulates Survival in Neonatal Sepsis
por: Fallon, Eleanor A., et al.
Publicado: (2017)

Edaravone Dexborneol Downregulates Neutrophil Extracellular Trap Expression and Ameliorates Blood-Brain Barrier Permeability in Acute Ischemic Stroke
por: Huang, Yuanxiang, et al.
Publicado: (2022)

Morphologic spectrum of glial tumors: an increased trend towards oligodendroglial tumors in Pakistan
por: Hashmi, Atif Ali, et al.
Publicado: (2014)

Clinicopathologic features of triple negative breast cancers: an experience from Pakistan
por: Hashmi, Atif Ali, et al.
Publicado: (2014)

Arranging blood for elective thyroid surgeries: dilemma continues in the developing world
por: Faridi, Salman, et al.
Publicado: (2017)

A Very Rare Complication of Hepatitis A Infection: Acute Myocarditis—A Case Report with Literature Review
por: Allen, Olivia, et al.
Publicado: (2018)

Survival and Pulmonary Injury After Neonatal Sepsis: PD1/PDL1's Contributions to Mouse and Human Immunopathology
por: Fallon, Eleanor A., et al.
Publicado: (2021)

Insight to changing morphologic patterns of glomerulopathy in adult Pakistani patients: an institutional perspective
por: Hashmi, Atif Ali, et al.
Publicado: (2016)

A Small Molecule β2 Integrin Agonist Improves Chronic Kidney Allograft Survival by Reducing Leukocyte Recruitment and Accompanying Vasculopathy
por: Khan, Samia Q., et al.
Publicado: (2014)

The effect of pegbovigrastim on circulating neutrophil count in dairy cattle: A randomized controlled trial
por: Van Schyndel, Sabrina J., et al.
Publicado: (2018)

Diagnostic accuracy of Bethesda system for reporting thyroid cytopathology: an institutional perspective
por: Naz, Samreen, et al.
Publicado: (2014)

Diagnostic role of fine needle aspiration cytology (FNAC) in the evaluation of salivary gland swelling: an institutional experience
por: Naz, Samreen, et al.
Publicado: (2015)

Clinical pattern and spectrum of endometrial pathologies in patients with abnormal uterine bleeding in Pakistan: need to adopt a more conservative approach to treatment
por: Abid, Mariam, et al.
Publicado: (2014)

Proteomic and Phospho-Proteomic Profile of Human Platelets in Basal, Resting State: Insights into Integrin Signaling
por: Qureshi, Amir H., et al.
Publicado: (2009)

Barriers and facilitators towards recovery and health service utilization among Haredi Jews with mental illness
por: Whitley, R., et al.
Publicado: (2023)

Role of peritoneal washing cytology in ovarian malignancies: correlation with histopathological parameters
por: Naz, Samreen, et al.
Publicado: (2015)

Accuracy of intraoperative frozen section for the evaluation of ovarian neoplasms: an institutional experience
por: Hashmi, Atif Ali, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_1r7cs0grugmk8l4bruubpibf9k