Cargando…

Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction

BACKGROUND: Tetralogy of Fallot (TOF) is one of the congenital cardiac abnormality which occurs during embryonic time. Although surgical correction, especially early operation, is the best way to treat patients, still contributing factors in morbidity and mortality is controversial. The objective of...

Descripción completa

Detalles Bibliográficos
Autores principales: Amirghofran, Ahmad Ali, Badr, Jamshid, Jannati, Mansour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856006/
https://www.ncbi.nlm.nih.gov/pubmed/29544482
http://dx.doi.org/10.1186/s12893-018-0338-y
_version_ 1783307230265737216
author Amirghofran, Ahmad Ali
Badr, Jamshid
Jannati, Mansour
author_facet Amirghofran, Ahmad Ali
Badr, Jamshid
Jannati, Mansour
author_sort Amirghofran, Ahmad Ali
collection PubMed
description BACKGROUND: Tetralogy of Fallot (TOF) is one of the congenital cardiac abnormality which occurs during embryonic time. Although surgical correction, especially early operation, is the best way to treat patients, still contributing factors in morbidity and mortality is controversial. The objective of this study is to investigate potential factors which might be correlated with post-operative outcomes of TOF. METHODS: In this retrospective study, 349 monitored patients with TOF correction were selected. Median of age was 4 (0.66–8) year, 58% of patients were male and 42% were female. Time of inotropic drug, extubation time, and ICU stay were considered as post-operative outcomes which extension of each of them increased the risk of death. RESULTS: Ventricular septal defect enlargement was associated with longer extubation time and ICU stay. Higher ratio of pre-operative haematocrit was correlated with mortality (0.047). CONCLUSIONS: Results of this study demonstrated that haematocrit ratio before operation should be considered as a predictive factor, and patients with higher ratio of haematocrit require more care after operation. VSD enlargement is associated with longer extubation time and ICU stay.
format Online
Article
Text
id pubmed-5856006
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-58560062018-03-22 Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction Amirghofran, Ahmad Ali Badr, Jamshid Jannati, Mansour BMC Surg Research Article BACKGROUND: Tetralogy of Fallot (TOF) is one of the congenital cardiac abnormality which occurs during embryonic time. Although surgical correction, especially early operation, is the best way to treat patients, still contributing factors in morbidity and mortality is controversial. The objective of this study is to investigate potential factors which might be correlated with post-operative outcomes of TOF. METHODS: In this retrospective study, 349 monitored patients with TOF correction were selected. Median of age was 4 (0.66–8) year, 58% of patients were male and 42% were female. Time of inotropic drug, extubation time, and ICU stay were considered as post-operative outcomes which extension of each of them increased the risk of death. RESULTS: Ventricular septal defect enlargement was associated with longer extubation time and ICU stay. Higher ratio of pre-operative haematocrit was correlated with mortality (0.047). CONCLUSIONS: Results of this study demonstrated that haematocrit ratio before operation should be considered as a predictive factor, and patients with higher ratio of haematocrit require more care after operation. VSD enlargement is associated with longer extubation time and ICU stay. BioMed Central 2018-03-15 /pmc/articles/PMC5856006/ /pubmed/29544482 http://dx.doi.org/10.1186/s12893-018-0338-y Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Amirghofran, Ahmad Ali
Badr, Jamshid
Jannati, Mansour
Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction
title Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction
title_full Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction
title_fullStr Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction
title_full_unstemmed Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction
title_short Investigation of associated factors with post-operative outcomes in patients undergoing Tetralogy of Fallot correction
title_sort investigation of associated factors with post-operative outcomes in patients undergoing tetralogy of fallot correction
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856006/
https://www.ncbi.nlm.nih.gov/pubmed/29544482
http://dx.doi.org/10.1186/s12893-018-0338-y
work_keys_str_mv AT amirghofranahmadali investigationofassociatedfactorswithpostoperativeoutcomesinpatientsundergoingtetralogyoffallotcorrection
AT badrjamshid investigationofassociatedfactorswithpostoperativeoutcomesinpatientsundergoingtetralogyoffallotcorrection
AT jannatimansour investigationofassociatedfactorswithpostoperativeoutcomesinpatientsundergoingtetralogyoffallotcorrection