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Safety of high-dose daptomycin in patients with severe renal impairment

BACKGROUND: Treatment options are limited for infections due to multidrug-resistant Gram-positive pathogens. Daptomycin is a lipopeptide antibiotic with concentration-dependent killing characteristic and dose-dependent post-antibiotic effect. To achieve optimized pharma-codynamic effect, some expert...

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Detalles Bibliográficos
Autores principales:	Tai, Chih-Hsun, Shao, Chi-Hao, Chen, Chen-You, Lin, Shu-Wen, Wu, Chien-Chih
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856061/ https://www.ncbi.nlm.nih.gov/pubmed/29559785 http://dx.doi.org/10.2147/TCRM.S159587

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