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Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints

Adaptive designs for multi-armed clinical trials have become increasingly popular recently because of their potential to shorten development times and to increase patient response. However, developing response-adaptive designs that offer patient-benefit while ensuring the resulting trial provides a...

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Detalles Bibliográficos
Autores principales: Smith, Adam L., Villar, Sofía S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856359/
https://www.ncbi.nlm.nih.gov/pubmed/29551849
http://dx.doi.org/10.1080/02664763.2017.1342780

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