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Bayesian adaptive bandit-based designs using the Gittins index for multi-armed trials with normally distributed endpoints
Adaptive designs for multi-armed clinical trials have become increasingly popular recently because of their potential to shorten development times and to increase patient response. However, developing response-adaptive designs that offer patient-benefit while ensuring the resulting trial provides a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856359/ https://www.ncbi.nlm.nih.gov/pubmed/29551849 http://dx.doi.org/10.1080/02664763.2017.1342780 |