Cargando…

Alternative splicing after gene duplication drives CEACAM1-paralog diversification in the horse

BACKGROUND: The CEA gene family is one of the most rapidly evolving gene families in the human genome. The founder gene of the family is thought to be an ancestor of the inhibitory immune checkpoint molecule CEACAM1. Comprehensive analyses of mammalian genomes showed that the CEA gene family is subj...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mißbach, Sophie, Aleksic, Denis, Blaschke, Lisa, Hassemer, Timm, Lee, Kyung Jin, Mansfeld, Martin, Hänske, Jana, Handler, Johannes, Kammerer, Robert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856374/ https://www.ncbi.nlm.nih.gov/pubmed/29544443 http://dx.doi.org/10.1186/s12862-018-1145-x

Ejemplares similares

Natural selection supports escape from concerted evolution of a recently duplicated CEACAM1 paralog in the ruminant CEA gene family
por: Hänske, Jana, et al.
Publicado: (2020)

Recent expansion and adaptive evolution of the carcinoembryonic antigen family in bats of the Yangochiroptera subgroup
por: Kammerer, Robert, et al.
Publicado: (2017)

Comparative Studies on Duplicated foxl2 Paralogs in Spotted Knifejaw Oplegnathus punctatus Show Functional Diversification
por: Du, Xinxin, et al.
Publicado: (2023)

Whole‐genome duplications followed by tandem duplications drive diversification of the protein modifier SUMO in Angiosperms
por: Hammoudi, Valentin, et al.
Publicado: (2016)

Altered splicing of CEACAM1 in breast cancer: Identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms
por: Gaur, Shikha, et al.
Publicado: (2008)

Functional Diversification after Gene Duplication: Paralog Specific Regions of Structural Disorder and Phosphorylation in p53, p63, and p73
por: dos Santos, Helena G., et al.
Publicado: (2016)

Phylogenomics: Gene Duplication, Unrecognized Paralogy and Outgroup Choice
por: Roy, Scott William
Publicado: (2009)

CEACAM1 recognition by bacterial pathogens is species-specific
por: Voges, Maike, et al.
Publicado: (2010)

Functional diversification of sonic hedgehog paralog enhancers identified by phylogenomic reconstruction
por: Hadzhiev, Yavor, et al.
Publicado: (2007)

Functional Compensation of Mouse Duplicates by their Paralogs Expressed in the Same Tissues
por: Luzuriaga-Neira, Agusto, et al.
Publicado: (2022)

Molecular cytogenetic differentiation of paralogs of Hox paralogs in duplicated and re-diploidized genome of the North American paddlefish (Polyodon spathula)
por: Symonová, Radka, et al.
Publicado: (2017)

Splign: algorithms for computing spliced alignments with identification of paralogs
por: Kapustin, Yuri, et al.
Publicado: (2008)

Duplicated Paralogous Genes Subject to Positive Selection in the Genome of Trypanosoma brucei
por: Emes, Richard D., et al.
Publicado: (2008)

Duplicated ribosomal protein paralogs promote alternative translation and drug resistance
por: Malik Ghulam, Mustafa, et al.
Publicado: (2022)

Expansion of the circadian transcriptome in Brassica rapa and genome-wide diversification of paralog expression patterns
por: Greenham, Kathleen, et al.
Publicado: (2020)

CEACAM1-Mediated Inhibition of Virus Production
por: Vitenshtein, Alon, et al.
Publicado: (2016)

Did genome duplication drive the origin of teleosts? A comparative study of diversification in ray-finned fishes
por: Santini, Francesco, et al.
Publicado: (2009)

Gene Duplication and Fragment Recombination Drive Functional Diversification of a Superfamily of Cytoplasmic Effectors in Phytophthora sojae
por: Shen, Danyu, et al.
Publicado: (2013)

Perturbation of Lytic and Latent Gammaherpesvirus Infection in the Absence of the Inhibitory Receptor CEACAM1
por: Adler, Heiko, et al.
Publicado: (2009)

Extensive Local Gene Duplication and Functional Divergence among Paralogs in Atlantic Salmon
por: Warren, Ian A., et al.
Publicado: (2014)

Inter-paralog amino acid inversion events in large phylogenies of duplicated proteins
por: Pascarelli, Stefano, et al.
Publicado: (2022)

Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers
por: Blumenthal, Rosalyn D, et al.
Publicado: (2007)

Role of CEACAM1 and CEACAM20 in an In Vitro Model of Prostate Morphogenesis
por: Zhang, Hui, et al.
Publicado: (2013)

Functional Diversification of Paralogous Transcription Factors via Divergence in DNA Binding Site Motif and in Expression
por: Singh, Larry N., et al.
Publicado: (2008)

Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing
por: Johnson, Samantha T., et al.
Publicado: (2021)

Evolutionary Diversification of Plant Shikimate Kinase Gene Duplicates
por: Fucile, Geoffrey, et al.
Publicado: (2008)

In ovo omnia: diversification by duplication in fish and other vertebrates
por: Braasch, Ingo, et al.
Publicado: (2009)

Duplicate gene enrichment and expression pattern diversification in multicellularity
por: Padawer, Timothy, et al.
Publicado: (2012)

Rapid divergence and diversification of mammalian duplicate gene functions
por: Assis, Raquel, et al.
Publicado: (2015)

Duplication and Diversification of REPLUMLESS – A Case Study in the Papaveraceae
por: Zumajo-Cardona, Cecilia, et al.
Publicado: (2018)

Duplication and diversification of insulin genes in ray-finned fish
por: Irwin, David M.
Publicado: (2019)

Recurrent Duplication and Diversification of Acrosomal Fertilization Proteins in Abalone
por: Carlisle, J. A., et al.
Publicado: (2022)

Human Dominant Disease Genes Are Enriched in Paralogs Originating from Whole Genome Duplication
por: Singh, Param Priya, et al.
Publicado: (2014)

Deregulation of the CEACAM Expression Pattern Causes Undifferentiated Cell Growth in Human Lung Adenocarcinoma Cells
por: Singer, Bernhard B., et al.
Publicado: (2010)

T cell-mediated elimination of cancer cells by blocking CEACAM6–CEACAM1 interaction
por: Pinkert, Jessica, et al.
Publicado: (2021)

CEACAMs: their role in physiology and pathophysiology
por: Kuespert, Katharina, et al.
Publicado: (2006)

Comments on "Human Dominant Disease Genes Are Enriched in Paralogs Originating from Whole Genome Duplication"
por: Chen, Wei-Hua, et al.
Publicado: (2014)

Soluble CEACAM8 Interacts with CEACAM1 Inhibiting TLR2-Triggered Immune Responses
por: Singer, Bernhard B., et al.
Publicado: (2014)

Slipins: ancient origin, duplication and diversification of the stomatin protein family
por: Green, Jasper B, et al.
Publicado: (2008)

Duplication and Diversification of the Hypoxia-Inducible IGFBP-1 Gene in Zebrafish
por: Kamei, Hiroyasu, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_h8dk5sjhh9a2dn3v96lisl8bd7