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Synthetic pathways and processes for effective production of 5-hydroxytryptophan and serotonin from glucose in Escherichia coli

BACKGROUND: Tryptophan derivatives such as 5-hydroxytryptophan (5HTP) and serotonin are valuable molecules with pharmaceutical interest. 5HTP is presently mainly obtained by extraction from the plant Griffonia simplicifolia and serotonin is produced by chemical synthesis. A simple biotechnological m...

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Detalles Bibliográficos
Autores principales:	Mora-Villalobos, José-Aníbal, Zeng, An-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856393/ https://www.ncbi.nlm.nih.gov/pubmed/29568327 http://dx.doi.org/10.1186/s13036-018-0094-7

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