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A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign

Despite advancements in diagnostic tools, physical signs such as xanthelasmata, arcus corneae, facial wrinkles, and gray hair are useful indicators of underlying diseases. The presence of bilateral diagonal earlobe creases (DELCs), also known as Frank’s sign, correlates with a myriad of cardiovascul...

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Detalles Bibliográficos
Autores principales: Lin, Aung Naing, Lin, Kyawzaw, Kyaw, Htoo, Abboud, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856409/
https://www.ncbi.nlm.nih.gov/pubmed/29560293
http://dx.doi.org/10.7759/cureus.2080
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author Lin, Aung Naing
Lin, Kyawzaw
Kyaw, Htoo
Abboud, Joseph
author_facet Lin, Aung Naing
Lin, Kyawzaw
Kyaw, Htoo
Abboud, Joseph
author_sort Lin, Aung Naing
collection PubMed
description Despite advancements in diagnostic tools, physical signs such as xanthelasmata, arcus corneae, facial wrinkles, and gray hair are useful indicators of underlying diseases. The presence of bilateral diagonal earlobe creases (DELCs), also known as Frank’s sign, correlates with a myriad of cardiovascular diseases such as coronary artery disease, cerebrovascular disease, and peripheral vascular disease. The use of Frank’s sign as a bedside predictor of underlying coronary artery disease is controversial among clinicians. We report a case of a patient with bilateral DELCs found to have significant coronary artery disease during diagnostic coronary angiography for recurrent chest pain.
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spelling pubmed-58564092018-03-20 A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign Lin, Aung Naing Lin, Kyawzaw Kyaw, Htoo Abboud, Joseph Cureus Cardiology Despite advancements in diagnostic tools, physical signs such as xanthelasmata, arcus corneae, facial wrinkles, and gray hair are useful indicators of underlying diseases. The presence of bilateral diagonal earlobe creases (DELCs), also known as Frank’s sign, correlates with a myriad of cardiovascular diseases such as coronary artery disease, cerebrovascular disease, and peripheral vascular disease. The use of Frank’s sign as a bedside predictor of underlying coronary artery disease is controversial among clinicians. We report a case of a patient with bilateral DELCs found to have significant coronary artery disease during diagnostic coronary angiography for recurrent chest pain. Cureus 2018-01-17 /pmc/articles/PMC5856409/ /pubmed/29560293 http://dx.doi.org/10.7759/cureus.2080 Text en Copyright © 2018, Lin et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Cardiology
Lin, Aung Naing
Lin, Kyawzaw
Kyaw, Htoo
Abboud, Joseph
A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign
title A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign
title_full A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign
title_fullStr A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign
title_full_unstemmed A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign
title_short A Myth Still Needs to be Clarified: A Case Report of the Frank's Sign
title_sort myth still needs to be clarified: a case report of the frank's sign
topic Cardiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856409/
https://www.ncbi.nlm.nih.gov/pubmed/29560293
http://dx.doi.org/10.7759/cureus.2080
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