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Downregulation of lumican accelerates lung cancer cell invasion through p120 catenin

The overexpression of lumican has been found in lung cancer cells; however, the functional role of lumican in lung cancer cells remains unclear. In this study, we found lumican functioned as a tubulin-binding protein and the depletion of lumican by transfection with its specific shRNA increased lung...

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Detalles Bibliográficos
Autores principales: Yang, Cheng-Ta, Li, Jhy-Ming, Chu, Wing-Keung, Chow, Shu-Er
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856799/
https://www.ncbi.nlm.nih.gov/pubmed/29549325
http://dx.doi.org/10.1038/s41419-017-0212-3