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Evaluation of a Miniaturized Biologically Vascularized Scaffold in vitro and in vivo
In tissue engineering, the generation and functional maintenance of dense voluminous tissues is mainly restricted due to insufficient nutrient supply. Larger three-dimensional constructs, which exceed the nutrient diffusion limit become necrotic and/or apoptotic in long-term culture if not provided...
Autores principales: | Kress, Sebastian, Baur, Johannes, Otto, Christoph, Burkard, Natalie, Braspenning, Joris, Walles, Heike, Nickel, Joachim, Metzger, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5856827/ https://www.ncbi.nlm.nih.gov/pubmed/29549334 http://dx.doi.org/10.1038/s41598-018-22688-w |
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