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Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse
Mitral valve prolapse (MVP) is a common and benign condition. However, some anatomic forms have been recently associated with life-threatening ventricular arrhythmias and sudden cardiac death. Imaging MVP holds the promise of individualized MVP risk assessment. Noninvasive imaging techniques availab...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Magdi Yacoub Heart Foundation
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857061/ https://www.ncbi.nlm.nih.gov/pubmed/29644231 http://dx.doi.org/10.21542/gcsp.2018.4 |
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author | Fernández-Friera, Leticia Salguero, Rafael Vannini, Luca Argüelles, Ana Fidalgo Arribas, Fernando Solís, Jorge |
author_facet | Fernández-Friera, Leticia Salguero, Rafael Vannini, Luca Argüelles, Ana Fidalgo Arribas, Fernando Solís, Jorge |
author_sort | Fernández-Friera, Leticia |
collection | PubMed |
description | Mitral valve prolapse (MVP) is a common and benign condition. However, some anatomic forms have been recently associated with life-threatening ventricular arrhythmias and sudden cardiac death. Imaging MVP holds the promise of individualized MVP risk assessment. Noninvasive imaging techniques available today are playing an increasingly important role in the diagnosis, prognosis and monitoring of MVP. In this article, we will review the current evidence on arrhythmogenic MVP, with special focus on the utility of echocardiography and CMR for identifying benign and “malignant” forms of MVP. The clinical relevance of this manuscript lies in the value of imaging technology to improve MVP risk prediction, including those arrhythmic-MVP cases with a higher risk of sudden cardiac death. |
format | Online Article Text |
id | pubmed-5857061 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Magdi Yacoub Heart Foundation |
record_format | MEDLINE/PubMed |
spelling | pubmed-58570612018-04-11 Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse Fernández-Friera, Leticia Salguero, Rafael Vannini, Luca Argüelles, Ana Fidalgo Arribas, Fernando Solís, Jorge Glob Cardiol Sci Pract Review Article Mitral valve prolapse (MVP) is a common and benign condition. However, some anatomic forms have been recently associated with life-threatening ventricular arrhythmias and sudden cardiac death. Imaging MVP holds the promise of individualized MVP risk assessment. Noninvasive imaging techniques available today are playing an increasingly important role in the diagnosis, prognosis and monitoring of MVP. In this article, we will review the current evidence on arrhythmogenic MVP, with special focus on the utility of echocardiography and CMR for identifying benign and “malignant” forms of MVP. The clinical relevance of this manuscript lies in the value of imaging technology to improve MVP risk prediction, including those arrhythmic-MVP cases with a higher risk of sudden cardiac death. Magdi Yacoub Heart Foundation 2018-03-14 /pmc/articles/PMC5857061/ /pubmed/29644231 http://dx.doi.org/10.21542/gcsp.2018.4 Text en Copyright ©2018 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution license CC BY 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Fernández-Friera, Leticia Salguero, Rafael Vannini, Luca Argüelles, Ana Fidalgo Arribas, Fernando Solís, Jorge Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse |
title | Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse |
title_full | Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse |
title_fullStr | Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse |
title_full_unstemmed | Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse |
title_short | Mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse |
title_sort | mechanistic insights of the left ventricle structure and fibrosis in the arrhythmogenic mitral valve prolapse |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857061/ https://www.ncbi.nlm.nih.gov/pubmed/29644231 http://dx.doi.org/10.21542/gcsp.2018.4 |
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