The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts

BACKGROUND: Ovarian cancer constitutes one of the most lethal gynecologic malignancies for females. Currently, early detection strategies and therapeutic options for ovarian cancer are far from satisfactory, leading to high diagnosis rates at late stages and disease relapses. New avenues of therapy...

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Detalles Bibliográficos
Autores principales: Zhao, Linjie, Wang, Wei, Huang, Shuang, Yang, Zhengnan, Xu, Lian, Yang, Qilian, Zhou, Xiu, Wang, Jinjin, Shen, Qiuhong, Wang, Chenlu, Le, Xiaobing, Feng, Min, Zhou, Nianxin, Lau, Wayne Bond, Lau, Bonnie, Yao, Shaohua, Yi, Tao, Wang, Xin, Zhao, Xia, Wei, Yuquan, Zhou, Shengtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857099/
https://www.ncbi.nlm.nih.gov/pubmed/29548303
http://dx.doi.org/10.1186/s13059-018-1412-6

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