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Role of Parkin and endurance training on mitochondrial turnover in skeletal muscle

BACKGROUND: Parkin is a ubiquitin ligase that is involved in the selective removal of dysfunctional mitochondria. This process is termed mitophagy and can assist in mitochondrial quality control. Endurance training can produce adaptations in skeletal muscle toward a more oxidative phenotype, an outc...

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Detalles Bibliográficos
Autores principales: Chen, Chris Chin Wah, Erlich, Avigail T., Hood, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857114/
https://www.ncbi.nlm.nih.gov/pubmed/29549884
http://dx.doi.org/10.1186/s13395-018-0157-y