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Total RNA extraction from tissues for microRNA and target gene expression analysis: not all kits are created equal

BACKGROUND: microRNAs (miRNAs) are short non-coding RNAs that fine-tune gene expression. The aberrant expression of miRNAs is associated with many diseases and they have both therapeutic and biomarker potential. However, our understanding of their usefulness is dependent on the tools we have to stud...

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Detalles Bibliográficos
Autores principales: Brown, Rikki A. M., Epis, Michael R., Horsham, Jessica L., Kabir, Tasnuva D., Richardson, Kirsty L., Leedman, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857145/
https://www.ncbi.nlm.nih.gov/pubmed/29548320
http://dx.doi.org/10.1186/s12896-018-0421-6