Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin

The bivalent histone modification reader 53BP1 accumulates around DNA double-strand breaks (DSBs), where it dictates repair pathway choice decisions by limiting DNA end resection. How this function is regulated locally and across the cell cycle to channel repair reactions toward non-homologous end j...

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Detalles Bibliográficos
Autores principales: Pellegrino, Stefania, Michelena, Jone, Teloni, Federico, Imhof, Ralph, Altmeyer, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857200/
https://www.ncbi.nlm.nih.gov/pubmed/28564601
http://dx.doi.org/10.1016/j.celrep.2017.05.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857200/
https://www.ncbi.nlm.nih.gov/pubmed/28564601
http://dx.doi.org/10.1016/j.celrep.2017.05.016

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