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Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin
The bivalent histone modification reader 53BP1 accumulates around DNA double-strand breaks (DSBs), where it dictates repair pathway choice decisions by limiting DNA end resection. How this function is regulated locally and across the cell cycle to channel repair reactions toward non-homologous end j...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857200/ https://www.ncbi.nlm.nih.gov/pubmed/28564601 http://dx.doi.org/10.1016/j.celrep.2017.05.016 |