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Structural tract alterations predict down-stream tau accumulation in amyloid positive older individuals

Animal models of Alzheimer’s disease (AD) have suggested that tau pathology propagation, facilitated by amyloid pathology, may occur along connected pathways. To investigate these ideas in humans, we combined amyloid scans with longitudinal data on white matter connectivity, hippocampal volume, tau...

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Detalles Bibliográficos
Autores principales:	Jacobs, Heidi I.L., Hedden, Trey, Schultz, Aaron P., Sepulcre, Jorge, Perea, Rodrigo D., Amariglio, Rebecca E., Papp, Kathryn V., Rentz, Dorene M., Sperling, Reisa A., Johnson, Keith A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857215/ https://www.ncbi.nlm.nih.gov/pubmed/29403032 http://dx.doi.org/10.1038/s41593-018-0070-z

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