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Mrgprs on vagal sensory neurons contribute to bronchoconstriction and airway hyperresponsiveness

Asthma, accompanied by lung inflammation, bronchoconstriction, and airway hyperresponsiveness, is a significant public health burden. Here we report that G protein-coupled receptor Mrgprs are expressed in a subset of vagal sensory neurons innervating the airway and mediates cholinergic bronchoconstr...

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Detalles Bibliográficos
Autores principales: Han, Liang, Limjunyawong, Nathachit, Ru, Fei, Li, Zhe, Hall, Olivia J., Steele, Haley, Zhu, Yuyan, Wilson, Julie, Mitzner, Wayne, Kollarik, Marian, Undem, Bradley J, Canning, Brendan J, Dong, Xinzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857222/
https://www.ncbi.nlm.nih.gov/pubmed/29403029
http://dx.doi.org/10.1038/s41593-018-0074-8

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