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Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess

INTRODUCTION: Ignavigranum ruoffiae is an extremely rare cause of human infections. CASE PRESENTATION: An 83-year-old male with a painless, ten-day-old, erythematous skin abscess on his left flank, which had showed a purulent discharge for 48 h, was admitted to the Emergency service. He was treated...

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Autores principales: De Paulis, Adriana N., Bertona, Eugenia, Gutiérrez, Miguel A., Ramírez, María S., Vay, Carlos A., Predari, Silvia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857363/
https://www.ncbi.nlm.nih.gov/pubmed/29568534
http://dx.doi.org/10.1099/jmmcr.0.005137
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author De Paulis, Adriana N.
Bertona, Eugenia
Gutiérrez, Miguel A.
Ramírez, María S.
Vay, Carlos A.
Predari, Silvia C.
author_facet De Paulis, Adriana N.
Bertona, Eugenia
Gutiérrez, Miguel A.
Ramírez, María S.
Vay, Carlos A.
Predari, Silvia C.
author_sort De Paulis, Adriana N.
collection PubMed
description INTRODUCTION: Ignavigranum ruoffiae is an extremely rare cause of human infections. CASE PRESENTATION: An 83-year-old male with a painless, ten-day-old, erythematous skin abscess on his left flank, which had showed a purulent discharge for 48 h, was admitted to the Emergency service. He was treated with cephalexin, disinfection with Codex water and spray of rifampicin. Five days later, surgical drainage of the abscess was proposed due to the torpid evolution of the patient. Samples were taken for culture, and antibiotic treatment with trimethoprim-sulfamethoxazole was established. The patient returned after 10 days showing healing of the abscess. Microbiological studies showed a few Gram-positive cocci present as single cells and short chains that grew after 72 h of incubation at 35 °C with CO(2) on 5 % sheep blood agar. Colonies presented a strong sauerkraut odour. Initial biochemical test results were negative for catalase, aesculin and bile-aesculin, and positive for pyrrolidonyl arylamidase, leucine aminopeptidase and growth in 6.5 % NaCl broth, which prompted the preliminary identification of Facklamia species or I. ruoffiae. The positive result for arginine deamination and negative result for hippurate hydrolysis, failure to produce acid from mannitol, sucrose, sorbitol or trehalose, plus the distinctive sauerkraut odour identified the organism as I. ruoffiae. The phenotypic identification was confirmed by 16S rRNA gene sequence analysis. The strain seemed to be susceptible to the antimicrobials tested but had decreased susceptibility to carbapenems. CONCLUSION: This case provides more insights into the phenotypic characteristics and antimicrobial resistance profile of I. ruoffiae.
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spelling pubmed-58573632018-03-22 Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess De Paulis, Adriana N. Bertona, Eugenia Gutiérrez, Miguel A. Ramírez, María S. Vay, Carlos A. Predari, Silvia C. JMM Case Rep Case Report INTRODUCTION: Ignavigranum ruoffiae is an extremely rare cause of human infections. CASE PRESENTATION: An 83-year-old male with a painless, ten-day-old, erythematous skin abscess on his left flank, which had showed a purulent discharge for 48 h, was admitted to the Emergency service. He was treated with cephalexin, disinfection with Codex water and spray of rifampicin. Five days later, surgical drainage of the abscess was proposed due to the torpid evolution of the patient. Samples were taken for culture, and antibiotic treatment with trimethoprim-sulfamethoxazole was established. The patient returned after 10 days showing healing of the abscess. Microbiological studies showed a few Gram-positive cocci present as single cells and short chains that grew after 72 h of incubation at 35 °C with CO(2) on 5 % sheep blood agar. Colonies presented a strong sauerkraut odour. Initial biochemical test results were negative for catalase, aesculin and bile-aesculin, and positive for pyrrolidonyl arylamidase, leucine aminopeptidase and growth in 6.5 % NaCl broth, which prompted the preliminary identification of Facklamia species or I. ruoffiae. The positive result for arginine deamination and negative result for hippurate hydrolysis, failure to produce acid from mannitol, sucrose, sorbitol or trehalose, plus the distinctive sauerkraut odour identified the organism as I. ruoffiae. The phenotypic identification was confirmed by 16S rRNA gene sequence analysis. The strain seemed to be susceptible to the antimicrobials tested but had decreased susceptibility to carbapenems. CONCLUSION: This case provides more insights into the phenotypic characteristics and antimicrobial resistance profile of I. ruoffiae. Microbiology Society 2018-01-16 /pmc/articles/PMC5857363/ /pubmed/29568534 http://dx.doi.org/10.1099/jmmcr.0.005137 Text en © 2018 The Authors http://creativecommons.org/licenses/by/4.0/ This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution and reproduction in any medium, provided the original author and source are credited.
spellingShingle Case Report
De Paulis, Adriana N.
Bertona, Eugenia
Gutiérrez, Miguel A.
Ramírez, María S.
Vay, Carlos A.
Predari, Silvia C.
Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess
title Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess
title_full Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess
title_fullStr Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess
title_full_unstemmed Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess
title_short Ignavigranum ruoffiae, a rare pathogen that caused a skin abscess
title_sort ignavigranum ruoffiae, a rare pathogen that caused a skin abscess
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857363/
https://www.ncbi.nlm.nih.gov/pubmed/29568534
http://dx.doi.org/10.1099/jmmcr.0.005137
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