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Neurturin Gene Therapy Protects Parasympathetic Function to Prevent Irradiation-Induced Murine Salivary Gland Hypofunction

Head and neck cancer patients treated with irradiation often present irreversible salivary gland hypofunction for which no conventional treatment exists. We recently showed that recombinant neurturin, a neurotrophic factor, improves epithelial regeneration of mouse salivary glands in ex vivo culture...

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Detalles Bibliográficos
Autores principales:	Ferreira, Joao N.A., Zheng, Changyu, Lombaert, Isabelle M.A., Goldsmith, Corinne M., Cotrim, Ana P., Symonds, Jennifer M., Patel, Vaishali N., Hoffman, Matthew P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857485/ https://www.ncbi.nlm.nih.gov/pubmed/29560384 http://dx.doi.org/10.1016/j.omtm.2018.02.008

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