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Elevated phospholipase D isoform 1 in Alzheimer's disease patients' hippocampus: Relevance to synaptic dysfunction and memory deficits

INTRODUCTION: Phospholipase D (PLD), a lipolytic enzyme that breaks down membrane phospholipids, is also involved in signaling mechanisms downstream of seven transmembrane receptors. Abnormally elevated levels of PLD activity are well-established in Alzheimer's disease (AD), implicating the two...

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Detalles Bibliográficos
Autores principales:	Krishnan, Balaji, Kayed, Rakez, Taglialatela, Giulio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Featured Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857521/ https://www.ncbi.nlm.nih.gov/pubmed/29560412 http://dx.doi.org/10.1016/j.trci.2018.01.002

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