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Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder
PURPOSE OF REVIEW: In this article, we aim to give an overview over recent neuroimaging research on dissociation in borderline personality disorder (BPD). Stress-related dissociation is highly prevalent in BPD, while so far only little is known about its neural underpinnings. RECENT FINDINGS: Based...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857558/ https://www.ncbi.nlm.nih.gov/pubmed/29577011 http://dx.doi.org/10.1007/s40473-018-0146-9 |
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author | Krause-Utz, Annegret Elzinga, Bernet |
author_facet | Krause-Utz, Annegret Elzinga, Bernet |
author_sort | Krause-Utz, Annegret |
collection | PubMed |
description | PURPOSE OF REVIEW: In this article, we aim to give an overview over recent neuroimaging research on dissociation in borderline personality disorder (BPD). Stress-related dissociation is highly prevalent in BPD, while so far only little is known about its neural underpinnings. RECENT FINDINGS: Based on research in depersonalization and the dissociative subtype of posttraumatic stress disorder, it has been proposed that dissociation involves alterations in a cortico-limbic network. In BPD, neuroimaging research explicitly focusing on dissociation is still scarce. SUMMARY: Functional neuroimaging studies have provided preliminary evidence for an altered recruitment and interplay of fronto-limbic regions (amygdala, anterior cingulate, inferior frontal gyrus, medial and dorsolateral prefrontal cortices) and temporoparietal areas (superior temporal gyrus, inferior parietal lobule, fusiform gyrus), which may underlie disrupted affective-cognitive processing during dissociation in BPD. More neuroimaging research with larger samples, clinical control groups, and repeated measurements is needed to deepen the understanding of dissociation in BPD. |
format | Online Article Text |
id | pubmed-5857558 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-58575582018-03-21 Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder Krause-Utz, Annegret Elzinga, Bernet Curr Behav Neurosci Rep Personality and Impulse Control Disorders (R Lee, Section Editor) PURPOSE OF REVIEW: In this article, we aim to give an overview over recent neuroimaging research on dissociation in borderline personality disorder (BPD). Stress-related dissociation is highly prevalent in BPD, while so far only little is known about its neural underpinnings. RECENT FINDINGS: Based on research in depersonalization and the dissociative subtype of posttraumatic stress disorder, it has been proposed that dissociation involves alterations in a cortico-limbic network. In BPD, neuroimaging research explicitly focusing on dissociation is still scarce. SUMMARY: Functional neuroimaging studies have provided preliminary evidence for an altered recruitment and interplay of fronto-limbic regions (amygdala, anterior cingulate, inferior frontal gyrus, medial and dorsolateral prefrontal cortices) and temporoparietal areas (superior temporal gyrus, inferior parietal lobule, fusiform gyrus), which may underlie disrupted affective-cognitive processing during dissociation in BPD. More neuroimaging research with larger samples, clinical control groups, and repeated measurements is needed to deepen the understanding of dissociation in BPD. Springer International Publishing 2018-02-12 2018 /pmc/articles/PMC5857558/ /pubmed/29577011 http://dx.doi.org/10.1007/s40473-018-0146-9 Text en © The Author(s) 2018 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Personality and Impulse Control Disorders (R Lee, Section Editor) Krause-Utz, Annegret Elzinga, Bernet Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder |
title | Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder |
title_full | Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder |
title_fullStr | Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder |
title_full_unstemmed | Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder |
title_short | Current Understanding of the Neural Mechanisms of Dissociation in Borderline Personality Disorder |
title_sort | current understanding of the neural mechanisms of dissociation in borderline personality disorder |
topic | Personality and Impulse Control Disorders (R Lee, Section Editor) |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857558/ https://www.ncbi.nlm.nih.gov/pubmed/29577011 http://dx.doi.org/10.1007/s40473-018-0146-9 |
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