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Ethyl pyruvate attenuates acetaminophen-induced liver injury and prevents cellular injury induced by N-acetyl-p-benzoquinone imine

Acetaminophen, a common analgesic/antipyretic, is a frequent cause of acute liver failure in Western countries. The development of an effective cure against acetaminophen hepatotoxicity is crucial. Ethyl pyruvate, an ethyl ester derivative of pyruvic acid, has been identified as a possible candidate...

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Detalles Bibliográficos
Autores principales: Nagatome, Minako, Kondo, Yuki, Kadowaki, Daisuke, Saishyo, Yusuke, Irikura, Mitsuru, Irie, Tetsumi, Ishitsuka, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857623/
https://www.ncbi.nlm.nih.gov/pubmed/29560444
http://dx.doi.org/10.1016/j.heliyon.2018.e00521