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Currently available murine Leydig cell lines can be applied to study early steps of steroidogenesis but not testosterone synthesis
Androgen biosynthesis in males occurs to a large extent in testicular Leydig cells. This study focused on the evaluation of three murine Leydig cell lines as potential screening tool to test xenobiotics interfering with gonadal androgen synthesis. The final step of testosterone (T) production in Ley...
Autores principales: | Engeli, Roger T., Fürstenberger, Cornelia, Kratschmar, Denise V., Odermatt, Alex |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857625/ https://www.ncbi.nlm.nih.gov/pubmed/29560447 http://dx.doi.org/10.1016/j.heliyon.2018.e00527 |
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