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The Trace Amine-Associated Receptor 1 Agonist 3-Iodothyronamine Induces Biased Signaling at the Serotonin 1b Receptor

Trace amine-associated receptors (TAARs) belong to the class A G-protein-coupled receptors (GPCR) and are evolutionary related to aminergic receptors. TAARs have been identified to mediate effects of trace amines. TAAR1 signaling is mainly mediated via activation of the G(s)/adenylyl cyclase pathway...

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Detalles Bibliográficos
Autores principales: Bräunig, Julia, Dinter, Juliane, Höfig, Carolin S., Paisdzior, Sarah, Szczepek, Michal, Scheerer, Patrick, Rosowski, Mark, Mittag, Jens, Kleinau, Gunnar, Biebermann, Heike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857711/
https://www.ncbi.nlm.nih.gov/pubmed/29593543
http://dx.doi.org/10.3389/fphar.2018.00222