Mucosal Delivery of Fusion Proteins with Bacillus subtilis Spores Enhances Protection against Tuberculosis by Bacillus Calmette-Guérin

Tuberculosis (TB) is the most deadly infectious disease in existence, and the only available vaccine, Bacillus Calmette-Guérin (BCG), is almost a century old and poorly protective. The immunological complexity of TB, coupled with rising resistance to antimicrobial therapies, necessitates a pipeline...

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Detalles Bibliográficos
Autores principales: Copland, Alastair, Diogo, Gil R., Hart, Peter, Harris, Shane, Tran, Andy C., Paul, Mathew J., Singh, Mahavir, Cutting, Simon M., Reljic, Rajko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857916/
https://www.ncbi.nlm.nih.gov/pubmed/29593708
http://dx.doi.org/10.3389/fimmu.2018.00346

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