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Different Conformational Subensembles of the Intrinsically Disordered Protein α-Synuclein in Cells

[Image: see text] The intrinsically disordered protein α-synuclein (αS) is thought to play an important role in cellular membrane processes. Although in vitro experiments indicate that this initially disordered protein obtains structure upon membrane binding, NMR and EPR studies in cells could not s...

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Detalles Bibliográficos
Autores principales: Fakhree, Mohammad A. A., Nolten, Ine Segers, Blum, Christian, Claessens, Mireille M. A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5857923/
https://www.ncbi.nlm.nih.gov/pubmed/29474083
http://dx.doi.org/10.1021/acs.jpclett.8b00092