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Insulin alleviates mitochondrial oxidative stress involving upregulation of superoxide dismutase 2 and uncoupling protein 2 in septic acute kidney injury

The aim of the present study was to explore the effects and mechanisms of insulin on mitochondrial oxidative stress in septic acute kidney injury (AKI). Male Sprague Dawley rats were divided randomly into four groups: Control group, sham surgery group, cecal ligation and puncture (CLP) group, and CL...

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Detalles Bibliográficos
Autores principales: Chen, Guang-Dao, Zhang, Jun-Liang, Chen, Yi-Ting, Zhang, Ju-Xing, Wang, Tao, Zeng, Qi-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858081/
https://www.ncbi.nlm.nih.gov/pubmed/29563990
http://dx.doi.org/10.3892/etm.2018.5890