Cargando…

Elevated Expression of miR302-367 in Endothelial Cells Inhibits Developmental Angiogenesis via CDC42/CCND1 Mediated Signaling Pathways

Rationale: Angiogenesis is critical for embryonic development and microRNAs fine-tune this process, but the underlying mechanisms remain incompletely understood. Methods: Endothelial cell (EC) specific miR302-367 line was used as gain-of-function and anti-miRs as loss-of-function models to investiga...

Descripción completa

Detalles Bibliográficos
Autores principales: Pi, Jingjiang, Liu, Jie, Zhuang, Tao, Zhang, Lin, Sun, Huimin, Chen, Xiaoli, Zhao, Qian, Kuang, Yashu, Peng, Sheng, Zhou, Xiaohui, Yu, Zuoren, Tao, Ting, Tomlinson, Brian, Chan, Paul, Tian, Ying, Fan, Huimin, Liu, Zhongmin, Zheng, Xiangjian, Morrisey, Edward, Zhang, Yuzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858164/
https://www.ncbi.nlm.nih.gov/pubmed/29556338
http://dx.doi.org/10.7150/thno.21986