Receptor-targeted aptamer-siRNA conjugate-directed transcriptional regulation of HIV-1

Gene-based therapies represent a promising therapeutic paradigm for the treatment of HIV-1, as they have the potential to maintain sustained viral inhibition with reduced treatment interventions. Such an option may represent a long-term treatment alternative to highly active antiretroviral therapy....

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Detalles Bibliográficos
Autores principales: Zhou, Jiehua, Lazar, Daniel, Li, Haitang, Xia, Xin, Satheesan, Sangeetha, Charlins, Paige, O'Mealy, Denis, Akkina, Ramesh, Saayman, Sheena, Weinberg, Marc S., Rossi, John J., Morris, Kevin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858168/
https://www.ncbi.nlm.nih.gov/pubmed/29556342
http://dx.doi.org/10.7150/thno.23085

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