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Rhynchophylline Downregulates Phosphorylated cAMP Response Element Binding Protein, Nuclear Receptor-related-1, and Brain-derived Neurotrophic Factor Expression in the Hippocampus of Ketamine-induced Conditioned Place Preference Rats
BACKGROUND: Addiction to ketamine is becoming a serious public health issues, for which there exists no effective treatment. Rhynchophylline (Rhy) is an alkaloid extracted from certain Uncaria species that is well known for both its potent anti-addictive and neuroprotective properties. Increasing ev...
Autores principales: | Guo, Youli, Luo, Chaohua, Tu, Genghong, Li, Chan, Liu, Yi, Liu, Wei, Lam Yung, Ken Kin, Mo, Zhixian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858247/ https://www.ncbi.nlm.nih.gov/pubmed/29576706 http://dx.doi.org/10.4103/pm.pm_90_17 |
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