Cargando…

Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition

Background: To improve the regenerative capacity of aged individuals, we reconstituted bone marrow (BM) of aged mice with young Sca-1 cells, which repopulated cardiac progenitors and prevented cardiac dysfunction after a myocardial infarction (MI). However, the mechanisms involved were incompletely...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jiao, Li, Shu-Hong, Wu, Jun, Weisel, Richard D., Yao, Alina, Stanford, William L., Liu, Shi-Ming, Li, Ren-Ke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858499/ https://www.ncbi.nlm.nih.gov/pubmed/29556355 http://dx.doi.org/10.7150/thno.22788

Ejemplares similares

Young Bone Marrow Sca-1 Cells Rejuvenate the Aged Heart by Promoting Epithelial-to-Mesenchymal Transition: Erratum
por: Li, Jiao, et al.
Publicado: (2023)

Young Bone-Marrow Sca-1(+) Stem Cells Rejuvenate the Aged Heart and Improve Function after Injury through PDGFRβ-Akt pathway
por: Li, Shu-Hong, et al.
Publicado: (2017)

Long‐term repopulation of aged bone marrow stem cells using young Sca‐1 cells promotes aged heart rejuvenation
por: Li, Jiao, et al.
Publicado: (2019)

Young bone marrow Sca‐1 cells protect aged retina from ischaemia‐reperfusion injury through activation of FGF2
por: Shao, Zhengbo, et al.
Publicado: (2018)

Targeting aged bone marrow for systemic rejuvenation
por: Alibhai, Faisal J., et al.
Publicado: (2020)

Translating bone marrow rejuvenation from the bench to beside
por: Alibhai, Faisal J., et al.
Publicado: (2022)

Potential of bone marrow mesenchymal stem cells in rejuvenation of the aged skin of rats
por: Liu, Zhen, et al.
Publicado: (2017)

Rejuvenation of Senescent Bone Marrow Mesenchymal Stromal Cells by Pulsed Triboelectric Stimulation
por: Li, Gaocai, et al.
Publicado: (2021)

Aged Human Multipotent Mesenchymal Stromal Cells Can Be Rejuvenated by Neuron-Derived Neurotrophic Factor and Improve Heart Function After Injury
por: Song, Hui-Fang, et al.
Publicado: (2017)

Photobiomodulation has rejuvenating effects on aged bone marrow mesenchymal stem cells
por: Eroglu, Binnur, et al.
Publicado: (2021)

Limited rejuvenation of aged hematopoietic stem cells in young bone marrow niche
por: Kuribayashi, Wakako, et al.
Publicado: (2020)

Rectification of radiotherapy-induced cognitive impairments in aged mice by reconstituted Sca-1(+) stem cells from young donors
por: Wlodarek, Lukasz, et al.
Publicado: (2020)

SAT067 Bone Marrow-induced Epithelial-Mesenchymal Transition In Beta Cells
por: Lee, Jihyun
Publicado: (2023)

Cell fusion contributes to the rescue of apoptotic cardiomyocytes by bone marrow cells
por: Yang, Wei-Jian, et al.
Publicado: (2012)

Human ESC-sEVs alleviate age-related bone loss by rejuvenating senescent bone marrow-derived mesenchymal stem cells
por: Gong, Liangzhi, et al.
Publicado: (2020)

Understanding systemic factors in aging and rejuvenation
por: Alibhai, Faisal J., et al.
Publicado: (2020)

Epicardial epithelial-to-mesenchymal transition in injured heart
por: Zhou, Bin, et al.
Publicado: (2011)

Frequency of SCA8, SCA10, SCA12, SCA36, FXTAS and C9orf72 repeat expansions in SCA patients negative for the most common SCA subtypes
por: Aydin, Gülsah, et al.
Publicado: (2018)

Analysis of SCA8, SCA10, SCA12, SCA17 and SCA19 in patients with unknown spinocerebellar ataxia: a Thai multicentre study
por: Choubtum, Lulin, et al.
Publicado: (2015)

Young at Heart: Combining Strategies to Rejuvenate Endogenous Mechanisms of Cardiac Repair
por: Maghin, Edoardo, et al.
Publicado: (2020)

Therapeutic effects of conditioned medium from bone marrow-derived mesenchymal stem cells on epithelial-mesenchymal transition in A549 cells
por: Wang, Xin, et al.
Publicado: (2018)

Murine Sca1(+)Lin(−) bone marrow contains an endodermal precursor population that differentiates into hepatocytes
por: Oh, Keunhee, et al.
Publicado: (2015)

Epicardial Epithelial-to-Mesenchymal Transition in Heart Development and Disease
por: Krainock, Michael, et al.
Publicado: (2016)

Cortactin in Epithelial–Mesenchymal Transition
por: Ji, Rong, et al.
Publicado: (2020)

Differentiation-Associated MicroRNA Alterations in Mouse Heart-Derived Sca-1(+)CD31(−) and Sca-1(+)CD31(+) Cells
por: Wu, Qiong, et al.
Publicado: (2016)

Conversion of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition is mediated by oxygen concentration in pancreatic cancer cells
por: Chen, Shuo, et al.
Publicado: (2018)

Conversion of epithelial-to-mesenchymal transition to mesenchymal-to-epithelial transition is mediated by oxygen concentration in pancreatic cancer cells
por: Chen, Shuo, et al.
Publicado: (2022)

The tale of young blood rejuvenating the old
por: Chu, Xiaogang, et al.
Publicado: (2023)

Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges
por: Zhou, Xueke, et al.
Publicado: (2020)

Biochanin A extirpates the epithelial-mesenchymal transition in a human lung cancer
por: Wang, Yan, et al.
Publicado: (2018)

Editorial: Mesenchymal Stem Cell Senescence and Rejuvenation
por: Zhang, Yuelin, et al.
Publicado: (2021)

Reduced ischemic brain injury by partial rejuvenation of bone marrow cells in aged rats
por: Taguchi, Akihiko, et al.
Publicado: (2011)

Rejuvenating the blood and bone marrow to slow aging-associated cognitive decline and Alzheimer’s disease
por: Kang, Seokjo, et al.
Publicado: (2020)

Anti-Cancer Potential of Phytochemicals: The Regulation of the Epithelial-Mesenchymal Transition
por: Liu, Shuangyu, et al.
Publicado: (2023)

Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis
por: Usman, Saima, et al.
Publicado: (2021)

Differentially expressed microRNAs in bone marrow mesenchymal stem cell-derived microvesicles in young and older rats and their effect on tumor growth factor-β1-mediated epithelial-mesenchymal transition in HK2 cells
por: Wang, Yan, et al.
Publicado: (2015)

The Aging Heart: Mitophagy at the Center of Rejuvenation
por: Liang, Wenjing J., et al.
Publicado: (2020)

Uterus: A Unique Stem Cell Reservoir Able to Support Cardiac Repair via Crosstalk among Uterus, Heart, and Bone Marrow
por: Ludke, Ana, et al.
Publicado: (2022)

Involvement of epithelial–mesenchymal transition in liver fibrosis
por: Yu, Kangkang, et al.
Publicado: (2018)

Epithelial–Mesenchymal Transition Participates in the Formation of Vestibular Flat Epithelium
por: He, Lu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kkiarju0pjoh6mhc9guk5520m1