Long Non-coding MIR205HG Depletes Hsa-miR-590-3p Leading to Unrestrained Proliferation in Head and Neck Squamous Cell Carcinoma

Over 70% of head & neck squamous cell carcinoma (HNSCC) patients carry TP53 oncogenic mutations. Here we studied the role of specific tumor-derived mutant p53 proteins in the aberrant transcription of long non-coding (lnc) MIR205HG gene in head and neck cancer cells. Methods: To understand the r...

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Detalles Bibliográficos
Autores principales: Di Agostino, Silvia, Valenti, Fabio, Sacconi, Andrea, Fontemaggi, Giulia, Pallocca, Matteo, Pulito, Claudio, Ganci, Federica, Muti, Paola, Strano, Sabrina, Blandino, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858504/
https://www.ncbi.nlm.nih.gov/pubmed/29556360
http://dx.doi.org/10.7150/thno.22167

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