A paclitaxel prodrug with bifunctional folate and albumin binding moieties for both passive and active targeted cancer therapy

Folate receptor (FR) has proven to be a valuable target for chemotherapy using folic acid (FA) conjugates. However, FA-conjugated chemotherapeutics still have low therapeutic efficacy accompanied with side effects, resulting from complications such as short circulation half-life, limited tumor deliv...

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Detalles Bibliográficos
Autores principales: Shan, Lingling, Zhuo, Xin, Zhang, Fuwu, Dai, Yunlu, Zhu, Guizhi, Yung, Bryant C., Fan, Wenpei, Zhai, Kefeng, Jacobson, Orit, Kiesewetter, Dale O., Ma, Ying, Gao, Guizhen, Chen, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858514/
https://www.ncbi.nlm.nih.gov/pubmed/29556370
http://dx.doi.org/10.7150/thno.24382

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