α-Viniferin Improves Facial Hyperpigmentation via Accelerating Feedback Termination of cAMP/PKA-Signaled Phosphorylation Circuit in Facultative Melanogenesis

Rationale: cAMP up-regulates microphthalmia-associated transcription factor subtype M (MITF-M) and tyrosinase (Tyro) in the generation of heavily pigmented melanosomes. Here, we communicate a therapeutic mechanism of hyperpigmented disorder by α-viniferin, an active constituent of Caragana sinica. M...

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Detalles Bibliográficos
Autores principales: Yun, Cheong-Yong, Mi Ko, Seon, Pyo Choi, Yong, Kim, Beom Joon, Lee, Jungno, Mun Kim, Jae, Kim, Ju Yeon, Song, Jin Yong, Kim, Song-Hee, Hwang, Bang Yeon, Tae Hong, Jin, Han, Sang-Bae, Kim, Youngsoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858515/
https://www.ncbi.nlm.nih.gov/pubmed/29556371
http://dx.doi.org/10.7150/thno.24385

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858515/
https://www.ncbi.nlm.nih.gov/pubmed/29556371
http://dx.doi.org/10.7150/thno.24385

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