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Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction

Uncontrolled diabetes and acute coronary syndrome share a complex dynamic that results in significant ambiguity when interpreting biomarker elevations in this setting. This is concerning because myocardial infarction has been shown to be the most common cause of death in the first 24 hours of admiss...

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Autores principales: Odubanjo, Anthony A, Kalisetti, Rohini, Adrah, Robert, Ajenifuja, Adeniyi, Joseph, Blessey, Zaman, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858608/
https://www.ncbi.nlm.nih.gov/pubmed/29568222
http://dx.doi.org/10.1177/1179547618763356
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author Odubanjo, Anthony A
Kalisetti, Rohini
Adrah, Robert
Ajenifuja, Adeniyi
Joseph, Blessey
Zaman, Mohammed
author_facet Odubanjo, Anthony A
Kalisetti, Rohini
Adrah, Robert
Ajenifuja, Adeniyi
Joseph, Blessey
Zaman, Mohammed
author_sort Odubanjo, Anthony A
collection PubMed
description Uncontrolled diabetes and acute coronary syndrome share a complex dynamic that results in significant ambiguity when interpreting biomarker elevations in this setting. This is concerning because myocardial infarction has been shown to be the most common cause of death in the first 24 hours of admission for uncontrolled diabetes. Literature shows that elevation in cardiac biomarkers in patients with uncontrolled diabetes could be from viral myopericarditis, although a clear clinical significance is still lacking.(1) It is, however, clear that elevation in cardiac biomarkers portends a poor long-term prognosis in patients with uncontrolled diabetes mellitus. We present a rare case of myopericarditis in a middle-aged patient with uncontrolled diabetes. The patient had elevated troponin I level reaching a peak of 7.3 ng/mL with associated ST elevations on electrocardiography. Coronary angiogram was subsequently done revealing clean coronaries. To our knowledge, this is the first description of myopericarditis in uncontrolled diabetes without a known cause.
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spelling pubmed-58586082018-03-22 Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction Odubanjo, Anthony A Kalisetti, Rohini Adrah, Robert Ajenifuja, Adeniyi Joseph, Blessey Zaman, Mohammed Clin Med Insights Case Rep Case Report Uncontrolled diabetes and acute coronary syndrome share a complex dynamic that results in significant ambiguity when interpreting biomarker elevations in this setting. This is concerning because myocardial infarction has been shown to be the most common cause of death in the first 24 hours of admission for uncontrolled diabetes. Literature shows that elevation in cardiac biomarkers in patients with uncontrolled diabetes could be from viral myopericarditis, although a clear clinical significance is still lacking.(1) It is, however, clear that elevation in cardiac biomarkers portends a poor long-term prognosis in patients with uncontrolled diabetes mellitus. We present a rare case of myopericarditis in a middle-aged patient with uncontrolled diabetes. The patient had elevated troponin I level reaching a peak of 7.3 ng/mL with associated ST elevations on electrocardiography. Coronary angiogram was subsequently done revealing clean coronaries. To our knowledge, this is the first description of myopericarditis in uncontrolled diabetes without a known cause. SAGE Publications 2018-03-13 /pmc/articles/PMC5858608/ /pubmed/29568222 http://dx.doi.org/10.1177/1179547618763356 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Odubanjo, Anthony A
Kalisetti, Rohini
Adrah, Robert
Ajenifuja, Adeniyi
Joseph, Blessey
Zaman, Mohammed
Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction
title Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction
title_full Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction
title_fullStr Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction
title_full_unstemmed Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction
title_short Severe Myopericarditis in Diabetic Ketoacidosis—All Troponin are Not Myocardial Infarction
title_sort severe myopericarditis in diabetic ketoacidosis—all troponin are not myocardial infarction
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858608/
https://www.ncbi.nlm.nih.gov/pubmed/29568222
http://dx.doi.org/10.1177/1179547618763356
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