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A variant in the SCN10A enhancer may affect human mechanical pain sensitivity

Expression of Nav1.8, encoded by SCN10A, can affect pain transmission and thus mediate the human pain phenotype. In the current study, we assessed whether the variant rs6801957, located in the SCN10A enhancer region, may have the potential to affect human pain. Through dual-luciferase reporter assay...

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Detalles Bibliográficos
Autores principales:	Duan, Guangyou, Sun, Jiaoli, Li, Ningbo, Zheng, Hua, Guo, Shanna, Zhang, Yuhao, Wang, Qingli, Ying, Ying, Zhang, Mi, Huang, Penghao, Zhang, Xianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858611/ https://www.ncbi.nlm.nih.gov/pubmed/29448912 http://dx.doi.org/10.1177/1744806918763275

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