Efficient Acceleration of the Pair-HMMs Forward Algorithm for GATK HaplotypeCaller on Graphics Processing Units

GATK HaplotypeCaller (HC) is a popular variant caller, which is widely used to identify variants in complex genomes. However, due to its high variants detection accuracy, it suffers from long execution time. In GATK HC, the pair-HMMs forward algorithm accounts for a large percentage of the total exe...

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Detalles Bibliográficos
Autores principales: Ren, Shanshan, Bertels, Koen, Al-Ars, Zaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Review: Special Collection: Computational Bioinformatics Tools for Evolutionary Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858735/
https://www.ncbi.nlm.nih.gov/pubmed/29568218
http://dx.doi.org/10.1177/1176934318760543

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858735/
https://www.ncbi.nlm.nih.gov/pubmed/29568218
http://dx.doi.org/10.1177/1176934318760543

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