Cargando…

PLGA particulate subunit tuberculosis vaccines promote humoral and Th17 responses but do not enhance control of Mycobacterium tuberculosis infection

Tuberculosis places a staggering burden on human health globally. The new World Health Organisation End-TB Strategy has highlighted the urgent need for more effective TB vaccines to improve control of the disease. Protein-based subunit vaccines offer potential as safe and effective generators of pro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ashhurst, Anneliese S., Parumasivam, Thaigarajan, Chan, John Gar Yan, Lin, Leon C. W., Flórido, Manuela, West, Nicholas P., Chan, Hak-Kim, Britton, Warwick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5858788/ https://www.ncbi.nlm.nih.gov/pubmed/29554138 http://dx.doi.org/10.1371/journal.pone.0194620

Ejemplares similares

CXCR6-Deficiency Improves the Control of Pulmonary Mycobacterium tuberculosis and Influenza Infection Independent of T-Lymphocyte Recruitment to the Lungs
por: Ashhurst, Anneliese S., et al.
Publicado: (2019)

CXCR3 Provides a Competitive Advantage for Retention of Mycobacterium tuberculosis-Specific Tissue-Resident Memory T Cells Following a Mucosal Tuberculosis Vaccine
por: Armitage, Ellis, et al.
Publicado: (2023)

Mucosal delivery of a multistage subunit vaccine promotes development of lung-resident memory T cells and affords interleukin-17-dependent protection against pulmonary tuberculosis
por: Counoupas, Claudio, et al.
Publicado: (2020)

Boosting BCG with recombinant influenza A virus tuberculosis vaccines increases pulmonary T cell responses but not protection against Mycobacterium tuberculosis infection
por: Muflihah, Heni, et al.
Publicado: (2021)

Synthesis, Characterization and Biological Evaluation of New 3,5-Disubstituted-Pyrazoline Derivatives as Potential Anti-Mycobacterium tuberculosis H37Ra Compounds
por: Wong, Kok Tong, et al.
Publicado: (2021)

Antituberculosis activity, phytochemical identification of Costus speciosus (J. Koenig) Sm., Cymbopogon citratus (DC. Ex Nees) Stapf., and Tabernaemontana coronaria (L.) Willd. and their effects on the growth kinetics and cellular integrity of Mycobacterium tuberculosis H37Rv
por: Mohamad, Suriyati, et al.
Publicado: (2018)

The Secreted Lipoprotein, MPT83, of Mycobacterium tuberculosis Is Recognized during Human Tuberculosis and Stimulates Protective Immunity in Mice
por: Kao, Fan F., et al.
Publicado: (2012)

Enhancing immunogenicity of novel multistage subunit vaccine of Mycobacterium tuberculosis using PLGA:DDA hybrid nanoparticles and MPLA: Subcutaneous administration
por: Khademi, Farzad, et al.
Publicado: (2019)

Andrographis paniculata Dosage Forms and Advances in Nanoparticulate Delivery Systems: An Overview
por: Raman, Subashini, et al.
Publicado: (2022)

Eurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer
por: Jothi, Shankar, et al.
Publicado: (2023)

Particulate Mycobacterial Vaccines Induce Protective Immunity against Tuberculosis in Mice
por: Chen, Shuxiong, et al.
Publicado: (2021)

PLGA particulate delivery systems for subunit vaccines: Linking particle properties to immunogenicity
por: Silva, A. L., et al.
Publicado: (2016)

Immunity to Mycobacterium tuberculosis
por: Triccas, James A., et al.
Publicado: (2011)

Mycobacterium tuberculosis components expressed during chronic infection of the lung contribute to long-term control of pulmonary tuberculosis in mice
por: Counoupas, Claudio, et al.
Publicado: (2016)

Urban Air Pollution Particulates Suppress Human T-Cell Responses to Mycobacterium Tuberculosis
por: Ibironke, Olufunmilola, et al.
Publicado: (2019)

Mycobacterium Tuberculosis in Spinal Tuberculosis
por: Moon, Myung-Sang, et al.
Publicado: (2017)

Mycobacterium tuberculosis Zinc Metalloprotease-1 Elicits Tuberculosis-Specific Humoral Immune Response Independent of Mycobacterial Load in Pulmonary and Extra-Pulmonary Tuberculosis Patients
por: Vemula, Mani H., et al.
Publicado: (2016)

Humoral response to HspX and GlcB to previous and recent infection by Mycobacterium tuberculosis
por: Rabahi, Marcelo Fouad, et al.
Publicado: (2007)

Biomedical Applications of Polyhydroxyalkanoate in Tissue Engineering
por: Pulingam, Thiruchelvi, et al.
Publicado: (2022)

Analysis of humoral responses to proteins encoded by region of difference 1 of Mycobacterium tuberculosis in sarcoidosis in a high tuberculosis prevalence country
por: Agarwal, Ritesh, et al.
Publicado: (2012)

Characterization of the Protective Immune Responses Conferred by Recombinant BCG Overexpressing Components of Mycobacterium tuberculosis Sec Protein Export System
por: Nisa, Annuurun, et al.
Publicado: (2022)

Mycobacterium tuberculosis
por: Venketaraman, Vishwanath, et al.
Publicado: (2015)

Modulation of Mycobacterium tuberculosis-specific humoral immune responses is associated with Strongyloides stercoralis co-infection
por: Anuradha, Rajamanickam, et al.
Publicado: (2017)

Mycobacterium tuberculosis–derived circulating cell-free DNA in patients with pulmonary tuberculosis and persons with latent tuberculosis infection
por: Pan, Sheng-Wei, et al.
Publicado: (2021)

Mycobacterium tuberculosis requires glyoxylate shunt and reverse methylcitrate cycle for lactate and pyruvate metabolism
por: Serafini, Agnese, et al.
Publicado: (2019)

Protease-Based Subunit Vaccine in Mice Boosts BCG Protection against Mycobacterium tuberculosis
por: Junqueira-Kipnis, Ana Paula, et al.
Publicado: (2022)

50S subunit recognition and modification by the Mycobacterium tuberculosis ribosomal RNA methyltransferase TlyA
por: Laughlin, Zane T., et al.
Publicado: (2022)

Mycobacterium tuberculosis Drug Resistance, Abkhazia
por: Pardini, Manuela, et al.
Publicado: (2005)

Multi-Stage Tuberculosis Subunit Vaccine Candidate LT69 Provides High Protection against Mycobacterium tuberculosis Infection in Mice
por: Niu, Hongxia, et al.
Publicado: (2015)

PLGA Carriers for Controlled Release of Levofloxacin in Anti-Tuberculosis Therapy
por: Antonov, Evgeny N., et al.
Publicado: (2022)

Evaluation of the humoral immune response and cross reactivity against Mycobacterium tuberculosis of mice immunized with liposomes containing glycolipids of Mycobacterium smegmatis
por: Borrero, Reinier, et al.
Publicado: (2013)

Delta inulin-based adjuvants promote the generation of polyfunctional CD4(+) T cell responses and protection against Mycobacterium tuberculosis infection
por: Counoupas, Claudio, et al.
Publicado: (2017)

Evaluation of Humoral Immunity to Mycobacterium tuberculosis-Specific Antigens for Correlation with Clinical Status and Effective Vaccine Development
por: Niki, Mamiko, et al.
Publicado: (2015)

Stromal structure remodeling by B lymphocytes limits T cell activation in lymph nodes of Mycobacterium tuberculosis–infected mice
por: Daniel, Lina, et al.
Publicado: (2022)

Season and size of urban particulate matter differentially affect cytotoxicity and human immune responses to Mycobacterium tuberculosis
por: Sarkar, Srijata, et al.
Publicado: (2019)

Spoligotyping and Mycobacterium tuberculosis
por: Gori, Andrea, et al.
Publicado: (2005)

Neutrophils in Mycobacterium tuberculosis
por: Alcantara, Cheldon Ann, et al.
Publicado: (2023)

Interpreting very low Mycobacterium tuberculosis detected on Xpert Mycobacterium tuberculosis/rifampicin
por: Ajbani, Kanchan, et al.
Publicado: (2019)

Advances in Polyhydroxyalkanoate Nanocarriers for Effective Drug Delivery: An Overview and Challenges
por: Prakash, Priyanka, et al.
Publicado: (2022)

Cellular and Humoral Mechanisms Involved in the Control of Tuberculosis
por: Zuñiga, Joaquin, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_df36uh2fouh8nd7pn7v040fsio